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In the Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy Trial (STABILITY) and the Stabilization of Plaques using Darapladib — Thrombosis in Myocardial Infarction 52 (SOLID-TIMI 52) trial, interleukin-6 (IL-6) was significantly and independently associated with incident cardiovascular events, including cardiovascular death, myocardial infarction, and heart failure.

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