The research community is currently investigating several key questions regarding stem cell homeostasis: (i) Does mitochondrial impairment affect stem cell function in vivo, and can stem cells be a therapeutic target for diseases causing mitochondrial dysfunction? (ii) Is it possible to modulate cell fate identity only through metabolic-related changes, and are these mechanisms relevant in vivo? (iii) Can the relationship between energy metabolism, cellular proliferation, and mitochondrial dynamics be untangled? (iv) What is the importance of calcium balance for cell fate plasticity? (v) How can redox homeostasis be effectively targeted to enhance stem cell function and improve efficient differentiation?

Authors

• Person: Not available Organization: Springer
  Mitochondria and the dynamic control of stem cell homeostasis

Sources

• Mitochondria and the dynamic control of stem cell homeostasis link.springer.com Springer via serper

Referenced by nodes (3)

• mitochondrial dynamics concept
• energy metabolism concept
• mitochondrial dysfunction concept