In experiments using the Open Field test, 5 mg/kg of DOI failed to boost the head-twitch response (HTR) in mice with a 5-HT2BR knockout, and 20 mg/kg of MDMA failed to increase the locomotor response in the same genotype compared to control mice, suggesting 5-HT2BR may play a significant role in the behavioral effects of psychedelics.

Authors

• Person: Not available Organization: Springer
  Effects of psychedelics on neurogenesis and broader neuroplasticity

Sources

• Effects of psychedelics on neurogenesis and broader neuroplasticity link.springer.com Springer via serper

Referenced by nodes (2)

• MDMA concept
• DOI concept