Metformin directly inhibits mTORC1 to improve stemness and alleviate senescence in stem cells, such as reversing aging-associated characteristics in intestinal stem cells.

Authors

• Person: Not available Organization: Nature
  Cellular rejuvenation: molecular mechanisms and potential ... - Nature

Sources

• Cellular rejuvenation: molecular mechanisms and potential ... - Nature www.nature.com Nature via serper

Referenced by nodes (3)

• mTORC1 concept
• metformin concept
• intestinal stem cells concept