Long-term partial reprogramming in physiologically aging mice rejuvenates tissues such as the skin and kidneys and the organism as a whole, characterized by a reversion of the epigenetic clock and metabolic and transcriptomic changes, including decreased expression of genes mediating inflammation, senescence, and stress response pathways.

Authors

• Person: Not available Organization: Nature
  Cellular rejuvenation: molecular mechanisms and potential ... - Nature

Sources

• Cellular rejuvenation: molecular mechanisms and potential ... - Nature www.nature.com Nature via serper

Referenced by nodes (1)

• partial reprogramming concept