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Van Maris and co-workers evolved a S. cerevisiae strain with deficient pyruvate decarboxylase activity for high-glucose tolerance, which was later attributed to an in-frame deletion in the glucose regulator MTH1 that altered the stability of the MTH1-encoded protein.
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Sources
- Adaptive laboratory evolution – principles and applications for ... link.springer.com via serper
Referenced by nodes (1)
- Saccharomyces cerevisiae concept