When a bacterium binds to surface receptors on a macrophage, it simultaneously triggers intracellular signaling that activates the transcription of pro-inflammatory cytokine genes in the nucleus, leading to the production and secretion of cytokines that act on nearby cells.

Authors

• Person: Not available Organization: Linus Pauling Institute
  Immunity In Depth | Linus Pauling Institute

Sources

• Immunity In Depth | Linus Pauling Institute lpi.oregonstate.edu Linus Pauling Institute via serper

Referenced by nodes (3)

• macrophages concept
• cytokines concept
• pro-inflammatory cytokine genes concept