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The relationship is established because protein intake is investigated as a dietary intervention for the treatment of obesity in a randomized trial, as documented in [1].
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Origins and evolution of the Western diet: health implications for the ... academia.edu 1 fact
referenceSkov AR, Toubro S, Ronn B, Holm L, and Astrup A conducted a randomized trial comparing protein versus carbohydrate in an ad libitum fat-reduced diet for the treatment of obesity, as published in the International Journal of Obesity and Related Metabolic Disorders in 1999.