Relations (1)

related 2.58 — strongly supporting 5 facts

The Sleep Heart Health Study identified a significant association between sleep-disordered breathing and hypertension [1], [2], and specifically found that the likelihood of hypertension increases with higher apnea-hypopnea index levels [3]. Furthermore, the study utilized hypertension as a key confounding factor when analyzing the relationship between sleep apnea and cardiovascular disease [4], [5].

Facts (5)

Sources
Extent and Health Consequences of Chronic Sleep Loss and ... - NCBI ncbi.nlm.nih.gov Colten HR, Altevogt BM · National Academies Press 5 facts
claimThe fact that adjusting for hypertension in the Sleep Heart Health Study did not eliminate the association between obstructive sleep apnea and cardiovascular disease suggests that hypertension is not the exclusive mechanism by which obstructive sleep apnea leads to cardiovascular disease.
claimNieto et al. (2000) identified an association between sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study known as the Sleep Heart Health Study.
referenceThe Sleep Heart Health Study is a community-based multicenter study of more than 6,000 middle-aged and older adults that measured the apnea-hypopnea index via polysomnography and found that the likelihood of hypertension was greater at higher apnea-hypopnea index levels.
claimThe Sleep Heart Health Study determined the apnea-hypopnea index using polysomnography and adjusted for confounding factors, including hypertension, finding that the association between obstructive sleep apnea and cardiovascular disease persisted even after adjusting for hypertension.
claimThe Sleep Heart Health Study, published in the Journal of the American Medical Association in 2000, found an association between sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study.