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related 0.50 — strongly supporting 5 facts
Psilocybin is being investigated as a potential therapeutic intervention for disorders of consciousness, as evidenced by computational simulations showing it can shift brain activity toward more complex and flexible dynamics [1], [2], [3]. Researchers propose that these psychedelic effects may help increase conscious awareness in patients [4], with studies utilizing personalized brain models to validate these potential clinical outcomes [5].
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A virtual clinical trial of psychedelics to treat patients with disorders ... eurekalert.org 3 facts
referenceAlnagger et al. published a study in the journal Advanced Science that utilized personalized computational models of patients' brains, constructed from individual functional MRI and diffusion-weighted imaging scans, to virtually simulate the effects of LSD and psilocybin on patients with disorders of consciousness.
claimThe simulation of LSD and psilocybin on patients with disorders of consciousness boosted the patients' responses to perturbations.
claimThe virtual clinical trial conducted by Alnagger et al. demonstrated that LSD and psilocybin could shift brain activity in patients with disorders of consciousness towards healthier, more flexible, and complex dynamics.
Psychedelics Assessed In New Virtual Clinical Trial - EMJ emjreviews.com 1 fact
claimIn patients with disorders of consciousness, the simulated use of LSD and psilocybin shifted brain activity towards more flexible and complex dynamics.
Psychedelics as a treatment for disorders of consciousness - PMC pmc.ncbi.nlm.nih.gov 1 fact
perspectiveThe authors of the paper 'Psychedelics as a treatment for disorders of consciousness' propose that psilocybin, a classic psychedelic, should be explored as a treatment to increase conscious awareness in patients with disorders of consciousness (DoC).