Relations (1)

related 2.00 — strongly supporting 3 facts

The Sleep Heart Health Study serves as a primary research source that investigates the clinical associations between obstructive sleep apnea and various health outcomes, such as cardiovascular disease [1], [2] and metabolic issues like insulin resistance [3].

Facts (3)

Sources
Extent and Health Consequences of Chronic Sleep Loss and ... - NCBI ncbi.nlm.nih.gov Colten HR, Altevogt BM · National Academies Press 3 facts
claimThe fact that adjusting for hypertension in the Sleep Heart Health Study did not eliminate the association between obstructive sleep apnea and cardiovascular disease suggests that hypertension is not the exclusive mechanism by which obstructive sleep apnea leads to cardiovascular disease.
claimObstructive sleep apnea (OSA) is associated with impaired glucose tolerance and insulin resistance, according to data from studies including the Sleep Heart Health Study (Ip et al., 2002; Punjabi et al., 2002; Punjabi et al., 2004).
claimThe Sleep Heart Health Study determined the apnea-hypopnea index using polysomnography and adjusted for confounding factors, including hypertension, finding that the association between obstructive sleep apnea and cardiovascular disease persisted even after adjusting for hypertension.