Knowledge Tree
Relations (1)
cross_type 2.32 — strongly supporting 4 facts
The spleen is anatomically and functionally linked to blood as it filters circulating blood to detect pathogens [1], receives a significant portion of cardiac output [2], and serves as a reservoir for immune cells that populate both the spleen and the blood [3]. Additionally, monocytes utilize the spleen's blood vessels to capture microorganisms [4].
Facts (4)
Sources
The immune system and primary immunodeficiency primaryimmune.org 2 facts
claimMature T cells leave the thymus as naïve T cells and populate organs such as the spleen, lymph nodes, bone marrow, and blood, where they may become memory T cells after antigen exposure.
claimMonocytes line the walls of blood vessels in organs like the liver and spleen to capture microorganisms passing through the blood.
Parts of the Immune System | Children's Hospital of Philadelphia chop.edu 2 facts
measurementApproximately 25 percent of the blood that comes from the heart flows through the spleen on every beat.
claimThe spleen filters circulating blood to detect pathogens, which triggers the activation and multiplication of immune system cells to neutralize those pathogens.