Knowledge Tree
Relations (1)
related 1.58 — strongly supporting 2 facts
Psilocybin reduces oscillatory activity in the Default Mode Network through decreased functional coupling between the medial prefrontal cortex and other components [1], and it alters functional connectivity of the medial prefrontal cortex in patients with treatment-resistant depression [2].
Facts (2)
Sources
The Mechanisms of Psychedelic Visionary Experiences - Frontiers frontiersin.org 1 fact
claimThe reduction in oscillatory activity and power in the Default Mode Network caused by psilocybin results from decreased functional coupling between the frontal cortex and the medial temporal lobe components of the Default Mode Network, as well as between the medial prefrontal cortex and the posterior cingulate cortex.
Neuroimaging in psychedelic drug development: past, present, and ... nature.com 1 fact
claimPatients with treatment-resistant depression treated with psilocybin showed differences in the functional connectivity of the medial pre-frontal cortex and hippocampus.