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Relations (1)
related 0.20 — supporting 2 facts
Medicinal plants are related to microorganisms because extracts from medicinal plants are evaluated for their ability to inhibit the growth of microorganisms in anti-infective procedures [1], and the concentration of active compounds in medicinal plants influences resistance development in microorganisms exposed to sublethal dosages [2].
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Medicinal plants: bioactive compounds, biological activities ... frontiersin.org 2 facts
claimThe concentration of active compounds in medicinal plants influences resistance development; while lower concentrations can diminish selective pressure, they may also facilitate adaptation if microorganisms encounter sublethal dosages that impede growth without causing mortality.
procedureThe procedure for evaluating medicinal plants for anti-infective properties involves: (1) selecting plant species based on traditional use, (2) subjecting the plants to extraction processes to obtain crude extracts or essential oils, (3) evaluating the extracts for their ability to inhibit the growth of harmful microorganisms, (4) confirming inhibitory activity via dose-dependent assays (MIC), (5) performing targeted assays to identify active constituents, (6) selecting and refining the most active fractions, and (7) using chemical testing and contemporary pharmacognosy to determine the composition of the final fraction.