Knowledge Tree
Relations (1)
related 2.58 — strongly supporting 5 facts
Allostatic load is defined as the cumulative wear and tear resulting from the chronic overactivity or inefficient management of the stress response system [1]. This relationship is further evidenced by the fact that allostatic load accumulates through the frequent activation and failed shut-down of the stress response system {fact:2, fact:5}, as well as sustained stress responses across various physiological systems [2].
Facts (5)
Sources
Understanding Allostasis: Stability Through Change - Cannelevate cannelevate.com.au 2 facts
claimAllostatic load accumulates through three primary mechanisms: frequent stress responses creating cumulative burden, failed shut-down of stress responses after stressors end, and inadequate physiological responses such as excessive inflammatory reactions or blunted cortisol release.
claimAllostatic load accumulates through three primary mechanisms: frequent stress responses (determined by magnitude and frequency), failed shut-down of stress responses after stressors end, and inadequate physiological responses (such as excessive inflammation or blunted cortisol release).
Integrating allostasis and emerging technologies to study complex ... nature.com 1 fact
claimSustained stress responses across neuroendocrine, immune, and metabolic systems drive allostatic load, which can lead to allostatic overload and multisystem dysfunction when prolonged.
Self-awareness, self-regulation, and self-transcendence (S-ART) frontiersin.org 1 fact
claimAllostatic load is defined as the cumulative wear and tear on the body and brain resulting from an overactive or inefficiently managed stress response (citing McEwen, 1998; Sterling and Eyer, 1988).
Homeostasis vs Allostasis — The Urban Health Council urbanhealthcouncil.com 1 fact
claimAllostatic load (AL) is a cumulative effect on the stress response caused by changes in mediators and physiological parameter levels resulting from daily routines, injury, disease, and aging.