Knowledge Tree
Relations (1)
related 2.00 — strongly supporting 3 facts
Ketamine is related to neurite outgrowth because it has been shown to promote this process through the upregulation of BDNF [1], with specific studies confirming that subanaesthetic doses enhance neurite growth in young adult mice [2], although the effect can be dose-dependent [3].
Facts (3)
Sources
Effects of psychedelics on neurogenesis and broader neuroplasticity link.springer.com 3 facts
claimKetamine exhibits a dual profile regarding neurogenesis and neural plasticity: it promotes synaptogenesis, neurite growth, and new neuron formation in single-dose paradigms, but high doses or neonatal exposure are linked to neurogenesis impairment and long-term cognitive deficits.
measurementKetamine enhances synaptogenesis and neurite growth in young adult mice when administered at subanaesthetic doses ranging from 0.25 to 10 mg/kg/day.
claimKetamine increases BDNF levels, which promotes synaptogenesis, neurite growth, and neurogenesis.