Knowledge Tree
Relations (1)
related 3.58 — strongly supporting 11 facts
The medial prefrontal cortex is a core anatomical component of the default mode network, as explicitly defined in [1] and [2]. This relationship is further supported by evidence detailing how the medial prefrontal cortex functions as a key node within the network during various states of consciousness and neural activity, as described in [3], [4], [5], and [6].
Facts (11)
Sources
The Mechanisms of Psychedelic Visionary Experiences - Frontiers frontiersin.org 8 facts
referenceBarrett and Griffiths (2017) identified parallels in the neural bases of psychedelic and meditative effects on the Default Mode Network (DMN), specifically hypothesizing that visionary experiences result from decreased activity and functional connectivity in the medial nodes of the DMN (PCC and MPFC), which mediate self-referential processing.
claimEpileptic seizures, including complex partial, generalized tonic-clonic, and absence seizures, impair primary nodes of the Default Mode Network (DMN), specifically the precuneus/PCC, medial frontal cortex, lateral parietal cortex, and the anterior cingulate cortex (ACC), resulting in long-lasting decreases in DMN activity.
claimThe reduction in oscillatory activity and power in the Default Mode Network caused by psilocybin results from decreased functional coupling between the frontal cortex and the medial temporal lobe components of the Default Mode Network, as well as between the medial prefrontal cortex and the posterior cingulate cortex.
referenceThe mirror neuron system (MNS) and the medial prefrontal cortex (mPFC) node of the default mode network (DMN) interact significantly during mentalizing and embodied simulation processes, according to Molnar-Szakacs and Uddin (2013).
referenceThe Default Mode Network (DMN) is based in the medial and lateral cortices of the parietal and temporal lobes, as well as the medial prefrontal cortex (mPFC), according to Raichle (2015).
referencePalhano-Fontes et al. (2015) found that ayahuasca consumption causes a significant decrease in activity throughout most parts of the Default Mode Network, particularly in the posterior cingulate cortex, precuneus, and medial prefrontal cortex, while also reducing functional connectivity within the posterior cingulate cortex/precuneus.
referenceWashington and VanMeter (2015) characterized the connectivity between the dorsal and ventral regions of the medial prefrontal cortex (mPFC) and the dorsal and ventral areas of the anterior cingulate cortex (ACC) as the most anterior area of functional connectivity within the default mode network (DMN).
referenceThe Default Mode Network primarily involves connections among the thalamus, posterior cingulate cortex (PCC), medial prefrontal cortex (mPFC), and areas of the limbic system (parahippocampal cortex and the hippocampus) that function as a network for information routing and integration, as described by Buckner et al. (2008).
A Synergistic Workspace for Human Consciousness Revealed by ... elifesciences.org 2 facts
claimRegions showing consistent decreases in ΦR during loss of consciousness were primarily members of the global synergistic workspace, specifically the default mode network (bilateral precuneus and medial prefrontal cortex) and bilateral inferior parietal cortex, with involvement of left temporal cortices.
claimThe default mode network (DMN) comprises the posterior cingulate, precuneus, medial prefrontal cortex, and inferior parietal cortices.
Ancient Roots of Today's Emerging Renaissance in ... link.springer.com 1 fact
claimClassic psychedelics initiate a cascade of altered neural connectivity and blood-flow across brain regions including the default-mode network (medial prefrontal cortex, posterior cingulate cortex, inferior parietal lobule, lateral temporal cortex, hippocampus, and precuneus), the amygdala, the thalamus, and the claustrum.