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Relations (1)
related 3.58 — strongly supporting 11 facts
The posterior cingulate cortex is a primary anatomical component and key hub of the default mode network, as established in [1], [2], and [3]. Furthermore, research into altered states of consciousness frequently highlights the posterior cingulate cortex as a specific node within the default mode network that experiences changes in activity and functional connectivity, as noted in [4], [5], [6], [7], [8], [9], and [10].
Facts (11)
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The Mechanisms of Psychedelic Visionary Experiences - Frontiers frontiersin.org 9 facts
referenceBarrett and Griffiths (2017) identified parallels in the neural bases of psychedelic and meditative effects on the Default Mode Network (DMN), specifically hypothesizing that visionary experiences result from decreased activity and functional connectivity in the medial nodes of the DMN (PCC and MPFC), which mediate self-referential processing.
claimEpileptic seizures, including complex partial, generalized tonic-clonic, and absence seizures, impair primary nodes of the Default Mode Network (DMN), specifically the precuneus/PCC, medial frontal cortex, lateral parietal cortex, and the anterior cingulate cortex (ACC), resulting in long-lasting decreases in DMN activity.
claimThe reduction in oscillatory activity and power in the Default Mode Network caused by psilocybin results from decreased functional coupling between the frontal cortex and the medial temporal lobe components of the Default Mode Network, as well as between the medial prefrontal cortex and the posterior cingulate cortex.
referenceThe 2016 review by dos Santos et al. reported a decrease in functional connectivity between key hubs of the Default Mode Network (DMN), specifically noting a reduction in connectivity between the posterior cingulate cortex (PCC) and the anterior cingulate cortex (ACC).
referenceHigh-hypnotizability subjects exhibit greater decreases in Default Mode Network (DMN) activity, particularly in the dorsal anterior cingulate cortex (ACC), and reduced connectivity between the posterior cingulate cortex (PCC) and the Executive Control Network, according to a 2017 study by Jiang et al.
referenceThe major subdivisions of the Default Mode Network include the ventral medial and dorsal medial regions of the prefrontal cortex, the posterior cingulate cortex (PCC) with the precuneus, and the lateral parietal cortex.
referencePalhano-Fontes et al. (2015) found that ayahuasca consumption causes a significant decrease in activity throughout most parts of the Default Mode Network, particularly in the posterior cingulate cortex, precuneus, and medial prefrontal cortex, while also reducing functional connectivity within the posterior cingulate cortex/precuneus.
claimThe interruption of the Default Mode Network (specifically the posterior cingulate cortex) by meditation, hypnosis, and epilepsy necessitates a general explanation for psychedelic effects within the broader context of altered consciousness.
referenceThe Default Mode Network primarily involves connections among the thalamus, posterior cingulate cortex (PCC), medial prefrontal cortex (mPFC), and areas of the limbic system (parahippocampal cortex and the hippocampus) that function as a network for information routing and integration, as described by Buckner et al. (2008).
Ancient Roots of Today's Emerging Renaissance in ... link.springer.com 1 fact
claimClassic psychedelics initiate a cascade of altered neural connectivity and blood-flow across brain regions including the default-mode network (medial prefrontal cortex, posterior cingulate cortex, inferior parietal lobule, lateral temporal cortex, hippocampus, and precuneus), the amygdala, the thalamus, and the claustrum.
A Synergistic Workspace for Human Consciousness Revealed by ... elifesciences.org 1 fact
claimThe default mode network (DMN) comprises the posterior cingulate, precuneus, medial prefrontal cortex, and inferior parietal cortices.