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granulosa cells ↔ ovulation

Relations (1)

related 2.00 — strongly supporting 3 facts

Ovulation serves as the physiological trigger that overcomes inhibitory factors affecting granulosa cells [1], [2], and subsequently initiates their transformation into the corpus luteum [3].

Facts (3)

Sources
The Normal Menstrual Cycle and the Control of Ovulation - NCBI - NIH ncbi.nlm.nih.gov Feingold KR, Adler RA, Ahmed SF · National Center for Biotechnology Information 3 facts
claimAfter ovulation, remaining granulosa cells enlarge, become vacuolated, and accumulate a yellow pigment called lutein, combining with theca-lutein cells and stroma to form the corpus luteum.
claimSpontaneous luteinization of granulosa cells can occur in the absence of luteinizing hormone (LH), suggesting that inhibitory factors like oocyte maturation inhibitor or luteinization inhibitor are overcome at ovulation.
claimSpontaneous luteinization of granulosa cells can occur in the absence of luteinizing hormone (LH), leading to the hypothesis that inhibitory factors like oocyte maturation inhibitor or luteinization inhibitor are overcome at ovulation.