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Relations (1)
related 2.58 — strongly supporting 5 facts
Berberine is a bioactive compound that exhibits antibacterial activity against Escherichia coli, as evidenced by its ability to kill multidrug-resistant strains [1], [2] and inhibit biofilm formation [3]. Furthermore, its effectiveness is quantified through minimum inhibitory concentration measurements [4] and it has been studied as an efflux pump inhibitor against specific proteins in Escherichia coli [5].
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Medicinal plants: bioactive compounds, biological activities ... frontiersin.org 4 facts
claimThe alkaloid berberine derived from apple inhibits biofilm formation in multidrug-resistant Escherichia coli by disrupting the synthesis of biofilm-related compounds.
claimBerberine, a bioactive compound found in Berberis vulgaris (barberry), is effective against the MDR microorganisms Escherichia coli and Staphylococcus aureus.
referenceLi and Ge (2023) published a study in Microbiology Spectrum on the role of berberine as a potential efflux pump inhibitor against MdfA from Escherichia coli using in vitro and in silico studies.
measurementThe minimum inhibitory concentration (MIC) range of berberine against diarrhea-associated bacteria, such as Staphylococcus aureus, MRSA, Vibrio cholera, Bacillus cereus, and Escherichia coli, is 12.5–469 µg/ml.
Pharmacological Uses of New Bioactive Compounds from Medicinal ... academia.edu 1 fact
claimThe bioactive compounds curcumin, allicin, and berberine are effective at killing multidrug-resistant bacteria, specifically Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa.