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• A moderate increase (20-percentile increase) in the AHEI score during follow-up was associated with a significantly lower risk of cardiovascular disease mortality and cancer mortality.
• Four non-communicable disease (NCD) dietary metrics—the Mediterranean Diet Score, Alternative Healthy Eating Index, Healthy Eating Index, and Dietary Approaches to Stop Hypertension—have convincing evidence of protective associations with specific NCD outcomes, including mortality, cardiovascular disease, type 2 diabetes, and total cancer.
• The Alternate Healthy Eating Index showed stronger associations with cardiovascular disease outcomes for both men and women compared to the original Healthy Eating Index, according to research by McCullough et al. (2000).
• Onvani S, Haghighatdoost F, Surkan PJ et al. (2017) published a meta-analysis in the Journal of Human Nutrition and Dietetics titled 'Adherence to the Healthy Eating Index and Alternative Healthy Eating Index dietary patterns and mortality from all causes, cardiovascular disease, and cancer: a meta-analysis of observational studies'.
• Pooled findings from two US cohorts found that the highest AHEI quintile (median 64.5) compared with the lowest quintile (median 36.9) was associated with a 24% reduction in cardiovascular disease, a 33% reduction in diabetes mellitus, and a 6% reduction in cancer incidence.