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Relations (1)
cross_type 2.00 — strongly supporting 3 facts
Europe is the geographic region where clinical studies on treatment-resistant depression have been conducted, as evidenced by the cohort study of patients across European countries [1], the cross-sectional study on the burden of the condition in Europe [2], and the European cohort study examining treatment patterns [3].
Facts (3)
Sources
The Montreal model: an integrative biomedical-psychedelic ... frontiersin.org 3 facts
referenceHeerlein et al. conducted a 2021 European cohort study published in the Journal of Affective Disorders examining treatment patterns and clinical outcomes for patients with treatment-resistant depression.
referenceJaffe et al. (2019) published 'The humanistic and economic burden of treatment-resistant depression in Europe: a cross-sectional study' in BMC Psychiatry.
measurementA 12-month cohort study of 411 patients with treatment-resistant depression across multiple European countries found that only about 30% of patients achieved a clinical response after 6–12 months of continual treatment.