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The brain and pro-inflammatory cytokines are related because in Alzheimer’s disease, the immune system's overreaction releases inflammatory cytokines that damage the brain [1].

Facts (1)

Sources
A Double-Edged Sword: Inflammation and Your Health - Cedars-Sinai cedars-sinai.org Cedars-Sinai 1 fact
claimIn Alzheimer’s disease, the immune system mistakenly targets plaques and tangles, causing it to overreact and release inflammatory cytokines that damage the brain.