hippocampus ↔ default mode network

Relations (1)

related 2.00 — strongly supporting 3 facts

The hippocampus is explicitly identified as a constituent region of the default mode network in both functional connectivity studies [1] and metabolic research [2], and it serves as a key component of the limbic system integration within this network [3].

Facts (3)

Sources

The Mechanisms of Psychedelic Visionary Experiences - Frontiers frontiersin.org Frontiers 2 facts

claimEgoless experiences, measured as 'oceanic boundlessness,' are associated with alterations in the frontolimbic-parieto-striatal network and are positively correlated with cerebral glucose metabolism in Default Mode Network regions (anterior cingulate cortex, hippocampus, inferior parietal cortex) and prefrontal cortex areas (frontomedial superior, frontolateral, and left inferolateral).

referenceThe Default Mode Network primarily involves connections among the thalamus, posterior cingulate cortex (PCC), medial prefrontal cortex (mPFC), and areas of the limbic system (parahippocampal cortex and the hippocampus) that function as a network for information routing and integration, as described by Buckner et al. (2008).

Ancient Roots of Today's Emerging Renaissance in ... link.springer.com Springer 1 fact

claimClassic psychedelics initiate a cascade of altered neural connectivity and blood-flow across brain regions including the default-mode network (medial prefrontal cortex, posterior cingulate cortex, inferior parietal lobule, lateral temporal cortex, hippocampus, and precuneus), the amygdala, the thalamus, and the claustrum.