Relations (1)

related 3.17 — strongly supporting 8 facts

Allostatic load is defined as the physiological wear and tear resulting from chronic stress, as established by McEwen's foundational work [1], [2]. This relationship is further supported by research linking stress as a primary driver of allostatic load in the context of cardiovascular disease [3], anxiety [4], and environmental factors like air pollution [5], [6].

Facts (8)

Sources
Homeostasis vs Allostasis — The Urban Health Council urbanhealthcouncil.com Urban Health Council 3 facts
referenceThe paper titled 'Air Pollution, Stress, and Allostatic Load: Linking Systemic and Central Nervous System Impacts' was published in the Journal of Alzheimer's Disease in 2019, spanning pages 597–614.
claimAir pollution and stress are linked to allostatic load and have systemic and central nervous system impacts, according to a 2019 study published in the Journal of Alzheimer's Disease.
referenceUllmann, E. et al. published 'From Allostatic Load to Allostatic State-An Endogenous Sympathetic Strategy to Deal With Chronic Anxiety and Stress?' in Front. Behav. Neurosci. in 2019.
Physiology, Homeostasis - StatPearls - NCBI Bookshelf ncbi.nlm.nih.gov National Library of Medicine 1 fact
referenceLogan JG and Barksdale DJ authored 'Allostasis and allostatic load: expanding the discourse on stress and cardiovascular disease' in J Clin Nurs in April 2008.
Self-awareness, self-regulation, and self-transcendence (S-ART) frontiersin.org Frontiers in Human Neuroscience 1 fact
referenceMcEwen, B. S. (1998) published 'Stress, adaptation, and disease. Allostasis and allostatic load' in Annals of the New York Academy of Sciences, volume 840, pages 33–44, discussing the concepts of allostasis and allostatic load in relation to stress and disease.
Associations Between Sleep Duration and Cognitive Function ... humanfactors.jmir.org JMIR Human Factors 1 fact
referenceMcEwen and Karatsoreos (2022) examined the impact of sleep deprivation and circadian disruption on stress, allostasis, and allostatic load.
Allostasis revisited: A perception, variation, and risk framework frontiersin.org Frontiers 1 fact
claimMcEwen (1998) introduced the concepts of allostasis and allostatic load in the context of stress, adaptation, and disease.
Integrating allostasis and emerging technologies to study complex ... nature.com Nature 1 fact
claimStress acts as a key driver of allostatic load within the immune system and can modulate various immune components.