Allostatic load ↔ adaptation

Relations (1)

related 2.00 — strongly supporting 3 facts

Allostatic load is defined as the physiological cost incurred by the body during the process of adaptation, as established by McEwen in his foundational work on stress and disease [1], [2], and [3].

Facts (3)

Sources

Allostasis revisited: A perception, variation, and risk framework frontiersin.org Frontiers 2 facts

quoteBruce McEwen described allostatic load as "the price of adaptation that promotes pathophysiology."

claimMcEwen (1998) introduced the concepts of allostasis and allostatic load in the context of stress, adaptation, and disease.

Self-awareness, self-regulation, and self-transcendence (S-ART) frontiersin.org Frontiers in Human Neuroscience 1 fact

referenceMcEwen, B. S. (1998) published 'Stress, adaptation, and disease. Allostasis and allostatic load' in Annals of the New York Academy of Sciences, volume 840, pages 33–44, discussing the concepts of allostasis and allostatic load in relation to stress and disease.