Knowledge Tree
Relations (1)
related 2.00 — strongly supporting 3 facts
Allostatic load is defined as a framework for understanding the physiological costs of stress, which includes the development of disease as a primary outcome {fact:1, fact:2}. Furthermore, disease is explicitly categorized as a perturbation-related cost within the allostatic load model [1].
Facts (3)
Sources
Allostasis revisited: A perception, variation, and risk framework frontiersin.org 2 facts
claimPerturbation-related costs (Eo) in the allostatic load framework are inherently unpredictable and include costs associated with injury, disease, unexpected wear-and-tear, habitat loss, habitat degradation, predation risk, and major weather events.
claimMcEwen (1998) introduced the concepts of allostasis and allostatic load in the context of stress, adaptation, and disease.
Self-awareness, self-regulation, and self-transcendence (S-ART) frontiersin.org 1 fact
referenceMcEwen, B. S. (1998) published 'Stress, adaptation, and disease. Allostasis and allostatic load' in Annals of the New York Academy of Sciences, volume 840, pages 33–44, discussing the concepts of allostasis and allostatic load in relation to stress and disease.