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Relations (1)
related 2.81 — strongly supporting 6 facts
Ketamine is clinically recognized for its efficacy in treating suicidality, as evidenced by its use in patients with severe depression and active suicidal ideation [1], [2], and [3]. Research and clinical models, such as the Montreal model, specifically address the administration of ketamine in the context of managing acute suicidality [4], [5], and [6].
Facts (6)
Sources
The Montreal model: an integrative biomedical-psychedelic ... frontiersin.org 5 facts
claimA randomized controlled trial (RCT) investigating music with ketamine found that both music and non-music interventions were effective and tolerable in a patient population characterized by high rates of comorbidity, suicidality, and chronicity.
claimKetamine is considered a putative psychedelic with several advantages, including a long medical track record, efficacy in treating severe Treatment-Resistant Depression (TRD) and suicidality, treatment sessions that are approximately 75% shorter than other psychedelic therapies, minimal drug–drug interactions, and safety in patients with bipolar affective disorder 1.
claimKetamine's rapid benefits against suicidality and the cognitive impairments of depression theoretically reduce obstacles to productive psychotherapy.
claimThe Montreal model for ketamine treatment excludes patients with active substance use due to potential iatrogenic harms, but does not exclude patients with personality disorders or acute suicidality, provided safety concerns are managed.
claimKetamine demonstrates safety and benefits in suboptimal real-world contexts, even without psychological support, and is effective for highly severe patients, including those with active suicidality and bipolar disorder.
Published Studies — Johns Hopkins Center for Psychedelic and ... hopkinspsychedelic.org 1 fact
referenceMathai, D. S., McCathern, A. G., Guzick, A. G., Schneider, S. C., Weinzimmer, S. A., Cepeda, S. L., Garcia-Romeu, A., and Storch, E. A. published 'Parental Attitudes Toward Use of Ketamine in Adolescent Mood Disorders and Suicidality' in the Journal of Child and Adolescent Psychopharmacology in 2021.