aging ↔ proteostasis network

Relations (1)

related 2.00 — strongly supporting 3 facts

The relationship between aging and the proteostasis network is established through extensive research, including reviews on their intersection with oxidative stress [1], lipid assemblies [2], and their fundamental role in the biological aging process [3].

Facts (3)

Sources

Cellular rejuvenation: molecular mechanisms and potential ... - Nature nature.com Nature 2 facts

referenceThe relationship between proteostasis, oxidative stress, and aging is reviewed in the 2017 paper 'Proteostasis, oxidative stress and aging' published in Redox Biology.

referenceLipid assemblies are at the intersection of aging, proteostasis, and neurodegeneration, as described in the 2019 paper 'Lipid assemblies at the crossroads of aging, proteostasis, and neurodegeneration' published in Trends in Cell Biology.

A unified framework for evolutionary genetic and physiological ... journals.plos.org PLOS Biology 1 fact

referenceLabbadia J and Morimoto RI published 'The Biology of Proteostasis in Aging and Disease' in the Annual Review of Biochemistry in 2015, detailing the role of proteostasis in the aging process and associated diseases.