Knowledge Tree
dentate gyrus
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Rusty Gage, PhD - Salk Institute salk.edu 12 facts
claimGenetic factors influence neurogenesis in the dentate gyrus of adult mice, according to research by Kempermann, Kuhn, and Gage published in 1997.
referenceL.S. Shihabuddin, P.J. Horner, J. Ray, and Rusty Gage published 'Adult spinal cord stem cells generate neurons after transplantation in the adult dentate gyrus' in the Journal of Neuroscience in 2000.
referenceG. Kempermann, E.P. Brandon, and F.H. Gage authored the paper 'Environmental stimulation of 129/SvJ mice causes increased cell proliferation and neurogenesis in the adult dentate gyrus' published in Current Biology in 1998 (Volume 8, Issue 16, pages 939-42).
referenceAdult-generated neurons in the dentate gyrus send axonal projections to field CA3 and are surrounded by synaptic vesicles, as reported in the 1999 Journal of Comparative Neurology.
referenceA 2004 study in Neuroscience by Farmer, Zhao, van Praag, Wodtke, Gage, and Christie examined the effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo.
referenceF.H. Gage, G. Kempermann, T.D. Palmer, D.A. Peterson, and J. Ray authored the paper 'Multipotent progenitor cells in the adult dentate gyrus' published in the Journal of Neurobiology in 1998 (Volume 36, Issue 2, pages 249-66).
referenceG. Buzsáki and F.H. Gage reported an absence of long-term potentiation in the subcortically deafferented dentate gyrus in a 1989 study published in Brain Research.
referenceH. van Praag, G. Kempermann, and Rusty Gage demonstrated that running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus, as published in the 1999 Nature Neuroscience.
referenceG. Kempermann, H.G. Kuhn, and F.H. Gage authored the paper 'Experience-induced neurogenesis in the senescent dentate gyrus' published in the Journal of Neuroscience in 1998 (Volume 18, Issue 9, pages 3206-12).
referenceReactive synaptogenesis, assessed by synaptophysin immunoreactivity, is associated with GAP-43 in the dentate gyrus of the adult rat, as reported by Masliah, Fagan, Terry, DeTeresa, Mallory, and Gage in a 1991 Experimental Neurology study.
referenceNeurogenesis in the dentate gyrus of the adult rat is characterized by an age-related decrease of neuronal progenitor proliferation, as reported in a 1996 study published in the Journal of Neuroscience.
referenceD.J. Clarke, F.H. Gage, O.G. Nilsson, and A. Björklund observed that grafted septal neurons form cholinergic synaptic connections in the dentate gyrus of behaviorally impaired aged rats, as published in the Journal of Comparative Neurology in 1986.