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Ecaterina Dumbrava
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How does targeted therapy treat cancer? | UT MD Anderson mdanderson.org Jun 7, 2024 5 facts
accountEcaterina Dumbrava reports that some patients at UT MD Anderson Cancer Center who were faced with a choice between hospice care and a clinical trial have been treated successfully for years using targeted therapies.
claimEcaterina Dumbrava expresses hope that the TP53 gene, known as the 'guardian of the genome,' will soon become a target for matched targeted therapies.
quoteEcaterina Dumbrava describes the mechanism of antibody drug conjugates as a 'Trojan horse,' noting that the chemotherapy drug remains inactive until it connects with the appropriate marker on the cancer cell.
claimEcaterina Dumbrava states that targeted therapies can significantly improve patient outcomes, prolong survival, and help maintain a good quality of life.
claimEcaterina Dumbrava, M.D., notes that KRAS was not previously considered a viable target for matched targeted therapies, which illustrates the rapid evolution of the field.