concept

Wnt signaling pathway

Also known as: Wnt signaling, Wnt signaling program, WNT signaling, WNT pathway

Facts (6)

Sources

Cellular rejuvenation: molecular mechanisms and potential ... - Nature nature.com Nature Mar 14, 2023 5 facts

referenceThe Wnt signaling pathway has a dual role during aging in Caenorhabditis elegans.

referenceWnt signaling is involved in bone, kidney, intestine, and adipose tissue maintenance and interorgan interaction during aging.

referenceWnt signaling plays a role in cardiovascular disease.

referencePolyphenols can target the Wnt signaling pathway, with implications for aging and age-related diseases.

referenceThe Wnt signaling pathway is involved in aging-related tissue fibrosis.

Dietary interventions as regulators of stem cell behavior in ... genesdev.cshlp.org Genes & Development 1 fact

claimBoth a high-fat diet and intermittent fasting lead to intestinal stem cell-autonomous activation of PPARδ signaling, which enhances self-renewal through partial activation of a Wnt signaling program and enhanced fatty acid oxidation.