concept

tumorigenesis

Also known as: tumorigenic process

Facts (8)

Sources

Cellular senescence: from homeostasis to pathological implications ... frontiersin.org Frontiers 2 facts

claimThe m6A reader YTHDF1 acts as a potential diagnostic biomarker and is involved in signaling pathways related to tumorigenesis and metastasis in pan-cancer.

claimK235 acetylation couples with PSPC1 to regulate the m(6)A demethylation activity of ALKBH5 and tumorigenesis.

Dietary interventions as regulators of stem cell behavior in ... genesdev.cshlp.org Genes & Development 2 facts

claimOncogenic mutations lock stem cells in states of ongoing self-renewal, which facilitates tumorigenesis, leading to the recognition of stem cells as the root of malignancy.

claimA high-fat diet endows progenitors in the intestinal crypt with stem cell properties, which may contribute to an enhanced propensity for tumorigenesis.

Mitochondria and the dynamic control of stem cell homeostasis link.springer.com Springer Apr 16, 2018 1 fact

referenceLee WTY and St. John JC proposed in 2016 that mitochondrial DNA acts as an initiator of tumorigenesis.

Inflammation bioxpedia.com BioXpedia 1 fact

claimCytokines and their receptors participate in diverse biological functions, including innate and adaptive immunity, inflammation, immune cell differentiation, angiogenesis, tumorigenesis, development, neurobiology, and viral pathogenesis.

Bioelectricity - The Levin Lab drmichaellevin.org drmichaellevin.org 1 fact

referenceB. T. Chernet, D. S. Adams, M. Lobikin, and Michael Levin published 'Use of genetically encoded, light-gated ion translocators to control tumorigenesis' in the journal Oncotarget in 2016.

Cellular rejuvenation: molecular mechanisms and potential ... - Nature nature.com Nature Mar 14, 2023 1 fact

referenceDu Pre et al. (2020) published 'Metabolic rivalry: circadian homeostasis and tumorigenesis' in Nature Reviews Cancer, discussing the interplay between circadian metabolic regulation and cancer development.