concept

tumor necrosis factor-alpha

Also known as: TNF, tumor necrosis factors, TNF-α, tumour necrosis factor-alpha, tumor necrosis factor

Facts (10)

Sources
Extent and Health Consequences of Chronic Sleep Loss and ... - NCBI ncbi.nlm.nih.gov Colten HR, Altevogt BM · National Academies Press 4 facts
referenceProinflammatory cytokines, including interleukin-1, tumor necrosis factor-α, and interleukin-6, possess somnogenic and pyrogenic properties and are linked to postdialytic symptoms such as daytime sleepiness and sleep disturbances (Konsman et al., 2002; Raison and Miller, 2001; Capuron et al., 2002).
claimInterleukin-1, tumor necrosis factor-α, and interleukin-6 are proinflammatory cytokines involved in hemodialysis-related symptoms, as identified by Pertosa et al. (2000).
referenceInterleukin-1, tumor necrosis factor-α, and interleukin-6 are identified as the major proinflammatory cytokines involved in the inflammatory response to hemodialysis (Pertosa et al., 2000).
claimCytokines used as biotherapy adjuncts, specifically interferon, interleukin-2, and tumor necrosis factor, are associated with side effects including daytime sleepiness, disturbed sleep, and depression.
What are Cytokines? Types & Function - Cleveland Clinic my.clevelandclinic.org Cleveland Clinic Jan 3, 2023 1 fact
claimTumor necrosis factor (TNF) is a cytokine that helps regulate inflammation and signals immune cells to kill tumor cells.
Research reveals devastating impact of Western diet on human health news-medical.net News-Medical.net Jun 18, 2023 1 fact
claimThe Western diet increases levels of inflammatory biomarkers, including C-reactive protein, interleukin 6 (IL-6), and tumor necrosis factor α (TNF-α).
Phytochemical and Pharmacological Studies of Traditionally Used ... heraldopenaccess.us Journal of Food Science & Nutrition 1 fact
claimVitex Negundo perturbs cancer-signaling pathways involving p38, p-ERK1/2, p-JNK, N-Terminal Kinase (JNK), COX-1, MAPK, tumor necrosis factor, vascular endothelial growth factor, and hypoxia-inducible factor in LPS-stimulated cells.
Understanding Allostasis: Stability Through Change - Cannelevate cannelevate.com.au CannElevate Jan 2, 2026 1 fact
claimInflammatory markers used to measure allostatic load include C-reactive protein, interleukin-6, fibrinogen, and tumour necrosis factor-alpha.
Pro-Inflammatory Cytokines Overview | Thermo Fisher Scientific - US thermofisher.com Thermo Fisher Scientific 1 fact
claimCytokines are categorized into interleukins (IL), chemokines, interferons, and tumor necrosis factors (TNF).
Short- and long-term health consequences of sleep disruption dovepress.com Goran Medic, Micheline Wille, Michiel EH Hemels · Dove Press May 19, 2017 1 fact
claimSleep abnormalities affect immune function by causing changes in proinflammatory cytokines, such as tumor necrosis factor, interleukins 1 and 6, and C-reactive protein.