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tryptamine
Also known as: tryptamine, tryptamines
Facts (15)
Sources
Effects of psychedelics on neurogenesis and broader neuroplasticity link.springer.com Dec 19, 2024 9 facts
claimThe systematic review categorized psychedelics into five main groups: CB1 agonists, NMDA antagonists, harmala alkaloids, tryptamines, and entactogens.
measurementAmong 18 original articles performing in vitro experiments, 52.6% utilized cannabinoid agonists and 21% utilized tryptamines.
measurementIn the sample of 51 original articles reporting in vivo experiments, the most commonly used psychedelics were cannabinoid agonists (29.4%), NMDA antagonists (27.4%), and tryptamines (17.6%).
measurementMost Brazilian articles on psychedelic research investigate the ayahuasca concoction or its main components, such as β-carbolines and tryptamines (n = 8).
claimPsychedelic compounds, including phenethylamines, tryptamines, and cannabinoids, are considered therapeutic options for neuropsychiatric disorders, with reports linking them to increased adult neurogenesis.
claimTryptamines are indolamine neurotransmitters that originate from the amino acid tryptophan (Araújo et al. 2015).
claimThe ayahuasca brew combines harmala alkaloids with psychoactive tryptamines and produces intense and prolonged intoxication effects.
referenceAraújo et al. (2015) published an updated review on the hallucinogenic properties and world of tryptamines.
referenceMcKenna, Towers, and Abbott (1984) published a study in the Journal of Ethnopharmacology identifying monoamine oxidase inhibitors, specifically tryptamine and β-carboline constituents, within the South American hallucinogenic plant preparation Ayahuasca.
“Plants of the Gods” and their hallucinogenic powers in ... surgicalneurologyint.com Jul 19, 2021 3 facts
claimTryptamine compounds are found in the secretions of toads, frogs, and certain fish, such as bufotenine, which is an open tryptamine found in the Anadenanthera tree and secreted in the skin of Bufo species of toads.
claimThe active chemical principle in Yopo tree (Anadenanthera) derivatives consists of tryptamine (indole alkaloids) neurochemicals related to serotonin.
quote“Visionary doses are 1 g of the dried mushroom, which contains approximately 1% tryptamine (e.g., psilocybin(e) and psilocin(e)."
Classification Schemes of Altered States of Consciousness - ORBi orbi.uliege.be 2 facts
referenceKay and Martin (1978) studied the effects of LSD and tryptamine on sleep/wakefulness and electrocorticogram patterns in intact cats, published in Psychopharmacology.
referenceAlexander and Ann Shulgin (2002) authored 'TIHKAL: The Continuation,' a text detailing the chemistry and subjective effects of tryptamines.
Hallucinogens | Springer Nature Link link.springer.com 1 fact
referenceThe article 'Hallucinogens as discriminative stimuli in animals: LSD, phenethylamines, and tryptamines' was authored by J.C. Winter and published in Psychopharmacology (Berl) in 2008, volume 203, issue 2, pages 251–263.