concept

TP53

Also known as: p53, TP53 gene

Facts (3)

Sources

Cellular rejuvenation: molecular mechanisms and potential ... - Nature nature.com Nature Mar 14, 2023 1 fact

claimTP53 and PTEN depletion causes luminal adenocarcinoma cells to trans-differentiate into neuroendocrine cells in prostate cancer.

How does targeted therapy treat cancer? | UT MD Anderson mdanderson.org MD Anderson Cancer Center Jun 7, 2024 1 fact

claimEcaterina Dumbrava expresses hope that the TP53 gene, known as the 'guardian of the genome,' will soon become a target for matched targeted therapies.

Clinical Center for Targeted Therapy | UT MD Anderson mdanderson.org MD Anderson Cancer Center 1 fact

claimDumbrava identifies the TP53 gene, known as the 'guardian of the genome,' as a potential future target for targeted therapies.