Knowledge Tree
tissue homeostasis
Facts (9)
Sources
Cellular rejuvenation: molecular mechanisms and potential ... - Nature nature.com Mar 14, 2023 5 facts
claimAltered intercellular communication is a hallmark of ageing, acting as a double-edged sword that contributes to both tissue homeostasis maintenance and age-related diseases.
claimStem cells and their cell microenvironments form a regenerative unit where stem cells maintain tissue homeostasis and the microenvironment regulates stem cell behavior.
claimAdult tissue-specific stem and progenitor cells utilize defensive mechanisms to reduce endogenous DNA damage, thereby maintaining genomic integrity and tissue homeostasis.
claimTissue-specific cells sense the chemical and mechanical characteristics of the extracellular microenvironment and produce responses that control cellular processes such as expansion, migration, differentiation, and activation to maintain tissue homeostasis.
claimThe depletion of the adult stem cell pool with age contributes to tissue degeneration, necessitating the replenishment of stem cell pools to maintain tissue homeostasis into old age.
Molecular mechanisms of cellular metabolic homeostasis in stem cells sciopen.com Dec 1, 2023 1 fact
claimUnderstanding the mechanisms that regulate metabolic homeostasis in stem cells may contribute to knowledge on how tissue homeostasis is maintained and provide insights for disease management.
Homeostasis and Health: From Balance to Change | Biological Theory link.springer.com Oct 14, 2025 1 fact
referenceO'Brien (2022) examines tissue homeostasis and non-homeostasis, ranging from cell life cycles to organ states.
Chronic inflammation in the etiology of disease across the life span nature.com Dec 5, 2019 1 fact
referenceSodium in the microenvironment regulates immune responses and tissue homeostasis, as reviewed by Muller et al. in a 2019 Nature Reviews Immunology article.
Cellular senescence: from homeostasis to pathological implications ... frontiersin.org 1 fact
referenceWu et al. (2023) published a study in Nature Aging regarding the m6A epitranscriptomic regulation of tissue homeostasis during primate aging.