Knowledge Tree
synaptic plasticity
Facts (12)
Sources
Effects of psychedelics on neurogenesis and broader neuroplasticity link.springer.com Dec 19, 2024 3 facts
claimPsychedelics produce electrophysiological changes that stimulate neurotrophic signaling, including the signaling of Brain-Derived Neurotrophic Factor (BDNF), which is a key promoter of synaptic plasticity and neuronal survival.
claimThe metabolite 2R,6R-hydroxynorketamine (2R,6R-HNK) may mediate the positive effects of ketamine, such as enhanced synaptic plasticity and increased BDNF levels, without causing the dissociative side effects associated with ketamine.
claimKetamine generally enhances neurogenesis and synaptic plasticity in adult subjects, which contrasts with the effects of high-dose ketamine in neonatal animals.
Psychedelics, Sociality, and Human Evolution frontiersin.org 1 fact
claimThe alteration of distributed neural processes by psychedelics manifests as increased synaptic plasticity and entropy, reduced integrity of discrete brain networks (such as the functional disintegration of the default-mode network), and reduced segregation between networks (such as increased functional connectivity between the default-mode network and the dorsal attention network).
Sleep duration, chronotype, health and lifestyle factors ... bmjpublichealth.bmj.com 1 fact
claimSevere sleep deprivation induces alterations in synaptic plasticity and impairments in learning and memory, which affects cognition.
Physiology, Sleep Stages - StatPearls - NCBI Bookshelf - NIH ncbi.nlm.nih.gov 1 fact
claimSleep spindles are believed to be integral to synaptic plasticity and are essential for procedural and declarative memory consolidation.
U shaped association between sleep duration and long ... nature.com by F Feng · 2025 1 fact
claimSleep deprivation disrupts synaptic plasticity, impairs long-term potentiation, and reduces dendritic spine density, which are essential for memory formation and consolidation.
Classification Schemes of Altered States of Consciousness - ORBi orbi.uliege.be 1 fact
referenceStephan, K.E., Friston, K.J., and Frith, C.D. (2009) proposed a model of dysconnection in schizophrenia, linking abnormal synaptic plasticity to failures of self-monitoring.
Self-awareness, self-regulation, and self-transcendence (S-ART) frontiersin.org 1 fact
referenceLabeling of epigenetic or transcription factors related to the expression of genes necessary for synaptic plasticity is indicative of extinction and reconsolidation processes, as reported by Sweatt (2009).
Conflicting States of Consciousness: Exploring Psilocin and Sleep psychedelicreview.com May 25, 2022 1 fact
quote“Our best understanding of psychedelic mechanism of action in mental disorders is anchored in synaptic plasticity, and synaptic plasticity is regulated by the sleep-wake cycle.”
The function(s) of consciousness: an evolutionary perspective frontiersin.org Nov 25, 2024 1 fact
claimSimple conditioning processes involving synaptic plasticity without memory are insufficient to confer agency on an individual, according to the analysis by Lacalli (2024).
The Mechanisms of Psychedelic Visionary Experiences - Frontiers frontiersin.org Sep 27, 2017 1 fact
claimProfound alterations of the brain's ordinary routines result in a greater randomization of brain activity, which allows for spontaneous synaptic plasticity that can reshape network connectivity and enhance overall coordination of neural activity.