concept

stem cells

Also known as: stem cell

Facts (15)

Sources

Pro-Inflammatory Cytokines Overview | Thermo Fisher Scientific - US thermofisher.com Thermo Fisher Scientific 5 facts

claimMacrophage colony-stimulating factor (M-CSF) is involved in adaptive immunity, produced by fibroblasts and endothelium, and binds to CD115 on stem cells to promote monocyte production and activation.

referenceG-CSF is classified as a pro-inflammatory cytokine, is produced by fibroblasts and endothelium, binds to the CD114 receptor, targets stem cells in the bone marrow, and functions in granulocyte production.

referenceGM-CSF is classified as an adaptive immunity cytokine, is produced by T cells, macrophages, and fibroblasts, binds to CD116 and CDw131 receptors, targets stem cells, and functions in the growth and differentiation of monocytes and the production of eosinophils and granulocytes.

referenceIL-3 is classified as an adaptive immunity cytokine, is produced by T cells, binds to CD123 and CDw131 receptors, targets stem cells, and functions in the proliferation and differentiation of hematopoietic precursors.

referenceIL-7 is classified as an adaptive immunity cytokine, is produced by bone marrow stromal cells and epithelial cells, binds to the CD127 receptor, targets stem cells, and functions as a B and T cell growth factor.

Parts of the Immune System | Children's Hospital of Philadelphia chop.edu Children's Hospital of Philadelphia 3 facts

claimAll immune system cells are created in the bone marrow from a common starting cell type called a stem cell.

claimBone marrow serves as the site where all immune system cells are created from a common starting cell type known as a stem cell.

claimStem cells in the bone marrow develop into red blood cells, platelets, and white blood cells.

How the Immune System Works with Primary Immunodeficiency igcares.com IGCares 2 facts

claimStem cells have the potential to differentiate and mature into the many different types of cells of the immune system.

claimBone marrow is the location where all cells of the immune system begin their development from primitive stem cells.

The Normal Menstrual Cycle and the Control of Ovulation - NCBI - NIH ncbi.nlm.nih.gov Feingold KR, Adler RA, Ahmed SF · National Center for Biotechnology Information Aug 5, 2018 2 facts

claimChan et al. confirmed the presence of stem cells in the human endometrium in 2004.

Global Versus Local Theories of Consciousness and the ... link.springer.com Springer 1 fact

claimA microphysiological system, such as an organoid, consists of stem cells in culture that differentiate and self-organize into a three-dimensional structure resembling a brain or parts of a brain.

The immune system and primary immunodeficiency primaryimmune.org Immune Deficiency Foundation 1 fact

claimB cells develop from stem cells in the bone marrow, where they undergo maturation and training to ensure they do not produce antibodies against healthy tissues.

Chronic inflammation in the etiology of disease across the life span nature.com Nature Dec 5, 2019 1 fact

claimMaternal inflammation contributes to brain overgrowth and autism-associated behaviors in offspring through altered redox signaling in stem and progenitor cells, according to a 2014 study by Le Belle et al.