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spermidine
Facts (6)
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Cellular senescence: from homeostasis to pathological implications ... frontiersin.org 6 facts
referenceSpermidine acts as a physiological autophagy inducer and may function as an anti-aging vitamin in humans, according to Madeo et al. in Autophagy (2019).
referenceSpermidine attenuates bleomycin-induced lung fibrosis in mice by inducing autophagy and inhibiting endoplasmic reticulum stress (ERS)-induced cell death, as found by Baek et al. in Experimental & Molecular Medicine (2020).
referenceThe induction of autophagy by spermidine promotes longevity, as demonstrated by Eisenberg et al. in Nature Cell Biology (2009).
referenceSpermidine induces autophagy and provides geroprotection through specific biological mechanisms, as detailed by Hofer et al. in Nature Aging (2022).
referenceSpermidine functions as an immune-modulating molecule with age-defying properties, as described by Chamoto et al. in Trends in Cell Biology (2024).
referenceSpermidine is essential for fasting-mediated autophagy and longevity, as reported by Hofer et al. in Nature Cell Biology (2024).