Knowledge Tree
Sleeping sickness
Also known as: African trypanosomiasis
Facts (12)
Sources
Extent and Health Consequences of Chronic Sleep Loss and ... - NCBI ncbi.nlm.nih.gov 12 facts
claimLundkvist GB, Kristensson K, and Bentivoglio M published a review in Physiology (Bethesda) in 2004 explaining why trypanosomes cause sleeping sickness.
claimSleeping sickness is characterized by episodes of nocturnal insomnia and daytime sleep, but not hypersomnia.
claimLundkvist GB, Kristensson K, and Bentivoglio M researched the biological mechanisms explaining why trypanosomes cause sleeping sickness.
claimSleeping sickness is primarily found in sub-Saharan African countries, where the Trypanosoma brucei parasite is transmitted to humans through bites from tsetse flies.
claimSleeping sickness, also known as African trypanosomiasis, is caused by infection with the Trypanosoma brucei (Tb) parasite.
claimIndividuals with sleeping sickness exhibit altered circadian fluctuations of the hormones cortisol, prolactin, and growth hormone.
claimSleeping sickness is associated with altered sleep architecture.
claimSleeping sickness, also known as African trypanosomiasis, occurs in individuals infected with the Trypanosoma brucei parasite.
claimResearchers hypothesize that sleeping sickness is a circadian rhythm disease that affects the neural pathways interconnecting the circadian-timing and sleep-regulating centers.
claimEEG recordings of individuals with sleeping sickness in Gambia show periods of REM sleep occurring throughout the entire sleep-wake cycle, often without normal intermediate NREM periods.
referenceBuguet A et al. reviewed the duality of sleeping sickness with a focus on sleep, published in Sleep Medicine Reviews in 2001.
claimCircadian fluctuations of cortisol, prolactin, and growth hormone are altered in individuals with sleeping sickness, according to Radomski et al. (1994).