Knowledge Tree
resveratrol
Facts (18)
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Medicinal plants and human health: a comprehensive review of ... link.springer.com Nov 5, 2025 10 facts
measurementCurcumin, genistein, and resveratrol block VEGF signaling pathways, which can reduce tumor blood flow by up to 70% and inhibit cancer spread.
claimResveratrol from red grapes, berberine from goldenseal, and quercetin from onions facilitate Th1 responses to augment cellular immunity while inhibiting excessive Th2 responses linked to allergic reactions.
referenceGu et al. (2021) conducted a multidimensional analysis of the antioxidative stress mechanisms behind resveratrol, published in the Journal of Food Quality.
measurementResveratrol derived from Vitis vinifera exhibits scavenging efficacy against hydroxyl radicals with an IC50 of 3.2 μM.
claimResveratrol inhibits chain propagation processes that exacerbate oxidative damage by generating stable quinone intermediates.
claimEpigallocatechin gallate (EGCG) from green tea, curcumin from turmeric, and resveratrol from red grapes inhibit amyloid-β aggregation and facilitate the removal of pre-existing plaques.
claimCurcumin, resveratrol from red grapes, and piperine from black pepper reduce the synthesis of pro-inflammatory cytokines TNF-α, IL-1β, and IL-6 while preserving neuronal integrity.
claimResveratrol derived from Vitis vinifera exhibits scavenging efficacy against hydroxyl radicals and superoxide anions due to its trans-stilbene configuration.
claimPolyphenolic compounds, specifically resveratrol and EGCG, induce apoptosis in cancer cells by depolarizing the mitochondrial membrane and releasing cytochrome c.
measurementCurcumin at dosages of 10–50 μM reduces microglial activation by 60–80% in LPS-stimulated mice, while resveratrol achieves comparable effects at 25–100 μM, according to Shahrajabian and Sun (2024).
Medicinal plants: bioactive compounds, biological activities ... frontiersin.org 5 facts
claimCompounds such as resveratrol and quercetin inhibit the expression of genes that encode virulence factors.
claimEl-Mahdy et al. (273) suggested that resveratrol and curcumin may serve as alternative treatment strategies for treating MRSA infections by diminishing toxin production.
referenceEl-Mahdy et al. (2023) examined the effect of resveratrol and curcumin on the gene expression of toxins produced by methicillin-resistant Staphylococcus aureus (MRSA).
referenceCui et al. (2024) reviewed recent advances in the use of resveratrol for treating Staphylococcus aureus infections.
claimResveratrol, derived from grapes, suppressed the synthesis of staphylococcal enterotoxins in methicillin-resistant Staphylococcus aureus (MRSA) (272).
Pharmacological Uses of New Bioactive Compounds from Medicinal ... academia.edu 2 facts
claimResveratrol acts as a factor that prevents skin aging and affects skin regeneration, according to a 2022 study by Leis, K., Pisanko, K., Jundziłł, A., Mazur, E., Męcińska-Jundziłł, K., and Witmanowski, H.
referencePolonini et al. (2013) studied the in vitro drug release and ex vivo percutaneous absorption of resveratrol cream using HPLC with a zirconized silica stationary phase, published in the Journal of Chromatography B.
Pharmacological Uses of New Bioactive Compounds from Medicinal ... ouci.dntb.gov.ua 1 fact
referenceLeis et al. (2022) examined resveratrol as a factor for preventing skin aging and affecting skin regeneration.