Knowledge Tree
relaxin
Facts (14)
Sources
Reproductive Hormones endocrine.org Jan 24, 2022 9 facts
claimIn women, relaxin levels increase after ovulation during the second half of the menstrual cycle to relax the uterine wall in preparation for pregnancy.
claimLow relaxin levels have been hypothesized to cause scleroderma, a condition characterized by the thickening and hardening of the skin, but this requires further study.
claimAt the end of pregnancy, relaxin helps relax the ligaments in the pelvis to allow the pelvis to stretch as the baby leaves the mother's body.
claimMen produce relaxin in the prostate gland, which is found in semen, but it does not circulate in the blood of men.
claimSome researchers have suggested that high relaxin levels may cause a pregnant woman's membranes to rupture, potentially leading to premature birth, though this has not been proven.
claimIf a woman does not conceive, relaxin levels drop until the next menstrual cycle.
claimIf conception occurs, relaxin levels increase throughout the first trimester to aid in implantation, placenta growth, and the prevention of uterine contractions.
claimRelaxin is a hormone secreted in the ovary by the corpus luteum, and during pregnancy, it is also released by the placenta and the uterine lining.
claimRelaxin has been shown to lessen tissue fibrosis in many organs, promote wound healing, and reduce blood pressure by relaxing blood vessels.
The Normal Menstrual Cycle and the Control of Ovulation - NCBI - NIH ncbi.nlm.nih.gov Aug 5, 2018 4 facts
claimLarge cells in the corpus luteum are more active in steroidogenesis and are influenced by autocrine/paracrine factors including inhibin, relaxin, and oxytocin.
claimThe human corpus luteum secretes relaxin, oxytocin, and progesterone, according to a 1989 study by Khan-Dawood et al. published in the Journal of Clinical Endocrinology & Metabolism.
claimThe role of luteotropic factors such as prolactin, oxytocin, inhibin, and relaxin in the menstrual cycle is unclear.
claimLarge luteal cells are more active in steroidogenesis and are influenced by autocrine/paracrine factors such as inhibin, relaxin, and oxytocin.
Expanding the evolutionary explanations for sex differences in the ... pubmed.ncbi.nlm.nih.gov May 2, 2020 1 fact
claimFemale pelves expand more than male pelves due to the effects of estrogen and relaxin produced by tissues in the pelvic region, and potentially due to the greater internal space occupied by female gonads and genitals.