Knowledge Tree
proanthocyanidins
Facts (12)
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Medicinal plants and human health: a comprehensive review of ... link.springer.com Nov 5, 2025 8 facts
claimPolyphenols from green tea and proanthocyanidins from grape seeds exhibit T-cell modulatory effects in models of autoimmune diseases by regulating transcription factors such as T-bet, GATA-3, and Foxp3.
claimProanthocyanidins derived from Vaccinium macrocarpon act as virucidal agents by directly inactivating viral particles and reducing infectious titers in cell culture systems.
claimSecondary metabolites, including catechins, proanthocyanidins, and ellagic acid, inhibit matrix metalloproteinases (MMPs) from degrading the extracellular matrix and invading tumors.
measurementProanthocyanidins derived from Vaccinium macrocarpon decrease herpes simplex viral load by 95% at a concentration of 50 μg/mL.
claimTheaflavins from black tea and proanthocyanidins from grape seeds exhibit significant anti-amyloid efficacy in both in vitro and in vivo settings.
claimTannins and proanthocyanidins possess antiviral properties by binding to viral envelope proteins, which obstructs early cellular attachment and membrane fusion.
claimProanthocyanidins derived from Vaccinium macrocarpon are effective against herpes simplex virus by inhibiting viral penetration.
claimTannins and proanthocyanidins exhibit broad-spectrum efficacy against enveloped viruses by inducing steric hindrance and conformational alterations of viral surface proteins through hydrogen bonding and hydrophobic interactions with viral glycoproteins.
Pharmacological Uses of New Bioactive Compounds from Medicinal ... academia.edu 2 facts
referenceAndersen-Civil et al. (2021) published a study in Communications Biology titled 'Structure-function analysis of purified proanthocyanidins reveals a role for polymer size in suppressing inflammatory responses,' which identifies that the size of proanthocyanidin polymers influences their ability to suppress inflammation.
referenceRauf et al. (2019) published a comprehensive review on proanthocyanidins in the journal Biomedicine & Pharmacotherapy.
Pharmacological Uses of New Bioactive Compounds from Medicinal ... ouci.dntb.gov.ua 1 fact
claimA. I. S. Andersen-Civil et al. (2021) found through structure-function analysis that the polymer size of purified proanthocyanidins plays a role in suppressing inflammatory responses.
Vernonia amygdalina: a comprehensive review of the ... frontiersin.org 1 fact
claimVernonia amygdalina contains numerous phytochemicals including alkaloids, glycosides, sesquiterpene lactones, steroids, flavonoids, proanthocyanidins, tannins, terpenoids, phenylpropanoids, resins, lignans, furocoumarines, naphthodianthrones, proteins, and peptides.