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primary insomnia
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Extent and Health Consequences of Chronic Sleep Loss and ... - NCBI ncbi.nlm.nih.gov 8 facts
claimLimbic and paralimbic structures that regulate basic emotions and instinctual behaviors—specifically the amygdala, hippocampus, ventromedial prefrontal cortex, and anterior cingulate cortex—are abnormally active during sleep in individuals with primary insomnia and secondary insomnias related to depression, as reported by Nofzinger et al. (2004a, 2005).
claimRiemann and Voderholzer (2003) identified primary insomnia as a potential risk factor for the development of depression.
referenceCharles M. Morin authored the chapter 'Psychological and behavioral treatments for primary insomnia' in the 4th edition of 'Principles and Practice of Sleep Medicine', published by Elsevier/Saunders in 2005.
claimIn primary insomnia patients, sleep-regulating structures in the central nervous system, specifically the brainstem, hypothalamus, and basal forebrain, are abnormally overactive during sleep, according to Nofzinger et al. (2004b).
referenceNowell et al. (1997) identified clinical factors that contribute to the differential diagnosis of primary insomnia versus insomnia related to mental disorders.
referenceA 2003 study by Riemann and Voderholzer published in the Journal of Affective Disorders examined whether primary insomnia acts as a risk factor for the development of depression.
referenceMorin (2005) discusses psychological and behavioral treatments for primary insomnia in the book 'Principles and Practice of Sleep Medicine'.
claimThe diagnostic criteria for primary insomnia include difficulty initiating or maintaining sleep or nonrestorative sleep, causing clinically significant distress or impairment in social or occupational functioning, not occurring exclusively during another sleep disorder, and not being due to the direct physiological effects of a substance or medical condition.
Impact of sleep duration on executive function and brain structure nature.com Mar 3, 2022 2 facts
measurementPrimary insomnia patients do not exhibit significant differences in hippocampal volume compared to good sleeper controls, according to a 2010 MRI volumetric study at 3 Tesla published in Sleep Medicine.
measurementWinkelman et al. conducted an MRI volumetric study at 3 Tesla and found no hippocampal volume differences between patients with primary insomnia and good sleeper controls.
Sleep Across the Lifespan: A Neurobehavioral Perspective link.springer.com Feb 5, 2025 1 fact
referenceHall et al. (2007) reported in Behavioral Sleep Medicine that psychological stress is associated with heightened physiological arousal during non-rapid eye movement (NREM) sleep in patients with primary insomnia.