Knowledge Tree
Plasma cells
Also known as: plasma cell
Facts (20)
Sources
The immune system and primary immunodeficiency primaryimmune.org 6 facts
claimWhen B cells encounter foreign germs (antigens), they mature into plasma cells to produce antibodies or into memory cells to facilitate a rapid response to future infections.
claimPeople fully immunized with live vaccine strains of the measles virus rarely catch the measles because they retain plasma cells and antibodies for many years, which prevent infection.
claimPlasma cells have a long lifespan, which enables the human body to retain immunity to viruses and bacteria encountered many years prior.
claimPlasma cells are the mature form of B cells that produce antibodies and are located in the spleen and lymph nodes.
claimPlasma cells collectively have the ability to produce antibodies against virtually all microbes in the environment, though each individual plasma cell produces only one kind of antibody.
claimFull immunization with live vaccine strains of the measles virus prevents future measles infection because the body retains plasma cells and antibodies for many years.
The components of the immune system - Immunobiology - NCBI - NIH ncbi.nlm.nih.gov 4 facts
claimThe B-cell antigen receptor (BCR) is a membrane-bound form of the antibody that a B cell will secrete after it activates and differentiates into a plasma cell.
claimB lymphocytes (B cells) differentiate into plasma cells that secrete antibodies upon activation.
claimB lymphocytes (B cells) differentiate into plasma cells that secrete antibodies upon activation.
claimThe B-cell antigen receptor (BCR) is a membrane-bound form of the antibody that the B cell will secrete after activation and differentiation into plasma cells.
Chronic Inflammation - StatPearls - NCBI Bookshelf ncbi.nlm.nih.gov 4 facts
claimChronic inflammation is characterized by the infiltration of primary inflammatory cells, specifically macrophages, lymphocytes, and plasma cells, into the tissue site.
claimNonspecific proliferative chronic inflammation is characterized by the presence of non-specific granulation tissue formed by the infiltration of mononuclear cells, such as lymphocytes, macrophages, and plasma cells, alongside the proliferation of fibroblasts, connective tissue, vessels, and epithelial cells, as seen in nasal or cervical polyps and lung abscesses.
claimIn chronic inflammation, infiltrating macrophages, lymphocytes, and plasma cells produce inflammatory cytokines, growth factors, and enzymes, which contribute to tissue damage progression and secondary repair processes such as fibrosis and granuloma formation.
claimThe hallmarks of chronic inflammation include the infiltration of primary inflammatory cells—specifically macrophages, lymphocytes, and plasma cells—into the tissue site, where they produce inflammatory cytokines, growth factors, and enzymes that contribute to tissue damage and secondary repair processes like fibrosis and granuloma formation.
How the Immune System Works with Primary Immunodeficiency igcares.com 3 facts
claimWhen B-cells encounter foreign material (antigens), they respond by maturing into plasma cells or memory cells, the latter of which allow a rapid response if the same infection is encountered again.
claimB-cells are lymphocytes that arise in the bone marrow and differentiate into plasma cells, which produce immunoglobulins (antibodies).
claimPlasma cells are the mature cells derived from B-cells that produce antibodies.
Pro-Inflammatory Cytokines Overview | Thermo Fisher Scientific - US thermofisher.com 2 facts
referenceIL-6 is classified as a pro-inflammatory cytokine, is produced by Th cells, macrophages, and fibroblasts, binds to CD126 and CD130 receptors, targets B cells and plasma cells, and functions in B-cell differentiation.
claimIL-6 stimulates several types of leukocytes and the production of acute phase proteins in the liver, and it is important in inducing B-cells to differentiate into antibody-forming plasma cells.
Parts of the Immune System | Children's Hospital of Philadelphia chop.edu 1 fact
claimB cells that secrete antibodies are also known as plasma cells.