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physiological systems
Also known as: physiological system, physiological organ systems, human physiological systems
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The New Field of Network Physiology: Building the Human ... frontiersin.org 26 facts
claimNetwork Physiology researchers intend to develop mathematical and computational methods to address the complexity of physiological systems and investigate emerging global behaviors in networks of dynamical systems.
referencePhysiological systems operate on time scales ranging from milliseconds to hours and exhibit oscillatory, stochastic, or mixed output dynamics, requiring an extension of earlier concepts that treated them as coupled chaotic oscillators (Ashkenazy et al., 2002; Chen et al., 2006; Xu et al., 2006).
referencePhysiological systems exhibit non-stationary, intermittent, scale-invariant, and nonlinear behaviors, as noted by Ivanov et al. (1999a) and Ivanov et al. (2001).
referenceThe journal Frontiers in Network Physiology covers networks comprised of diverse physiological systems and the associations between physiologic network structure and physiologic function.
referenceThe Human Physiolome is a dataset consisting of continuous long-term synchronous recordings from multiple physiological systems and corresponding blueprint reference network maps that represent physiologic interactions across temporal and spatial scales from the sub-cellular to the organism level.
claimThe output dynamics of physiological systems change over time in response to different physiologic states, pathologic conditions, and changes in underlying control mechanisms.
claimPhysiological systems communicate through complex mechanisms that manifest as various functional forms of coupling, necessitating the integration of pair-wise physiologic interactions into a general framework that combines nonlinear dynamics, information theory, and machine learning.
claimNetwork Physiology researchers posit that health emerges as a result of network interactions among physiological systems.
claimNetwork Physiology is currently in an early stage of development, characterized as a network building phase that requires broad-scale empirical investigations to establish a general framework for identifying and defining dynamical links among physiological systems.
claimPrinciples of interactions and network organization among physiological systems can be used to derive algorithms for next-generation intelligent electronic and robotic systems, as well as swarms of bots, to execute versatile and complex tasks.
referenceEach integrated physiological system exhibits multiple simultaneous interactions and varying forms of coupling with other systems that change over time (Bartsch and Ivanov, 2014; Bartsch et al., 2012; Bartsch et al., 2014).
claimThe field of Network Physiology aims to address how physiological systems synchronize and integrate their dynamics as a network to optimize functions and maintain health.
claimNetwork physiology investigates the role of synchronized bursting dynamics in mediating neural control and the flow of information between brain rhythms, neuronal populations, cortical rhythms, and other physiological organ systems.
referenceThe journal Frontiers in Network Physiology covers the study of cascades of failure across physiological systems as encountered in critical care.
claimChanges in the dynamics of individual physiological systems (network nodes) can propagate via time-varying, 'elastic' links to affect the dynamics of other nodes, thereby altering the behavior of the entire network.
claimPhysiologic states and functions emerge out of the collective dynamics of integrated physiological and organ systems.
claimThe field of Network Physiology aims to understand how diverse organs, physiological systems, and sub-systems dynamically interact as a network from the cellular to the organism level to produce various physiological states and functions in health and disease.
claimTemporal network approaches fail to account for the complex dynamics of individual physiological systems (network nodes) and the heterogeneity of physiological networks where coupling forms (network links) vary over time.
claimA central question in physiology is how physiological states and functions emerge from the collective network dynamics of integrated systems.
claimThe field of Network Physiology aims to establish an atlas of dynamic interactions among human physiological systems and lay the foundation for the Human Physiolome by uncovering principles of system integration and hierarchical network reorganization.
claimThe human organism is composed of various physiological and organ systems, each characterized by its own structural organization and functional complexity, which result in complex, transient, fluctuating, and nonlinear output dynamics.
claimThe human organism functions as an integrated network where multi-component physiological systems, each possessing its own regulatory mechanism, continuously interact to coordinate their functions.
claimCurrent temporal network methodologies are insufficient to address the complexity of physiological systems and the specific problems inherent to network physiology.
procedureRecent studies in Network Physiology have focused on four key areas: 1) investigating brain-brain network interactions across distinct brain rhythms and locations, 2) characterizing dynamical features of brain-organ communications as a new signature of neuro-autonomic control, 3) establishing basic principles underlying coordinated organ-organ communications, and 4) constructing first dynamic maps of physiological systems and organ interactions across distinct physiologic states.
claimA fundamental problem in physiological systems is understanding phenomena where global behaviors emerge from networked interactions among dynamically changing entities with nonlinear coupling forms that change over time.
referencePhysiological systems at the sub-cellular, tissue, and organism levels exhibit bursting dynamics resulting from molecular and cellular signaling processes (Ferrari et al., 2015).
Defining the Western Diet & Its Impact - Frontier Neuro frontierneuro.com Feb 1, 2022 1 fact
claimRefined sugar is broken down rapidly in the human body, causing insulin and blood sugar levels to spike, which negatively impacts physiological systems.