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neuronal membrane
Also known as: neuronal cell surface membranes
Facts (11)
Sources
Neuroanatomy, Neuron Action Potential - StatPearls - NCBI Bookshelf ncbi.nlm.nih.gov 5 facts
claimThe neuronal cell membrane's lipid bilayer functions as a capacitor, while transmembrane channels function as resistors in the generation of membrane potential.
claimNeurons in the human brain have an average of 1,000 synapses that influence the electrical potential of the neuronal membrane.
claimWider axons possess lower internal resistance, and a higher density of voltage-gated sodium channels in the neuronal membrane decreases membrane resistance, both of which affect action potential propagation speed.
claimThe speed of action potential propagation in neurons is influenced by the axon's internal contents and the electrical resistance of the neuronal membrane.
claimIon channels in the neuronal membrane are gated by second messengers, neurotransmitters, or voltage changes, allowing permeable ions to flow down their electrochemical gradients and alter the membrane potential.
Thinking about the action potential: the nerve signal as a window to ... frontiersin.org 5 facts
claimThe authors propose a framework that derives the physical manifestations of the action potential from a macroscopic, thermodynamics-based perspective, treating the nerve signal as a result of the collective physico-chemical properties of the lipid bilayer neuronal membrane (specifically the axolemma) and the membrane skeleton (cytoskeletal protein polymers, particularly actin fibrils).
claimFabiunke et al. (2020) conducted optical studies to examine the state of the neuronal membrane during the propagation of action potentials.
claimCultured neuronal cell surface membranes exhibit sharp, localized, and reversible phase transitions that are triggered by temperature changes and modified by pH levels.
referenceThe Hodgkin and Huxley model treats the neuronal membrane as a capacitor and ion channels as resistors, where changes in ionic conductance across the membrane cause a sudden and transient alteration of the transmembrane potential.
referenceAl-Rekabi et al. (2019) published research in Acta Biomaterialia titled 'Electrophysiological-mechanical coupling in the neuronal membrane and its role in ultrasound neuromodulation and general anaesthesia,' which explores the relationship between mechanical and electrical properties in neuronal membranes.
Action potential: Definition, Steps, Phases | Kenhub kenhub.com 1 fact
claimAn action potential propagates along the neuronal membrane by sequentially depolarizing adjacent segments of the membrane, effectively causing a new action potential in each subsequent segment rather than moving as a single entity.