concept

neurodegeneration

Also known as: neuronal degeneration

Facts (11)

Sources

Extent and Health Consequences of Chronic Sleep Loss and ... - NCBI ncbi.nlm.nih.gov Colten HR, Altevogt BM · National Academies Press 3 facts

claimNeurodegeneration in brain regions involved in regulating the sleep-wake cycle causes abnormalities that affect sleep patterns.

claimREM sleep behavior disorder is frequently associated with neurological disorders and may serve as an early sign of neurodegeneration.

claimSleep patterns are affected by abnormalities caused by neurodegeneration in brain regions involved in regulating the sleep-wake cycle.

Cellular senescence: from homeostasis to pathological implications ... frontiersin.org Frontiers 2 facts

referenceNAD+ levels are implicated in aging, metabolism, and neurodegeneration, as detailed by E. Verdin in a 2015 article in Science.

referenceChandramowlishwaran, P., Vijay, A., Abraham, D., Li, G., Mwangi, S., Srinivasan, S. (2020) examined the role of sirtuins in modulating neurodegeneration of the enteric nervous system and central nervous system, published in Frontiers in Neuroscience.

Cellular rejuvenation: molecular mechanisms and potential ... - Nature nature.com Nature Mar 14, 2023 2 facts

referenceMontaruli et al. (2020) published 'The wrinkling of time: Aging, inflammation, oxidative stress, and the circadian clock in neurodegeneration' in Neurobiology of Disease, examining the intersection of aging, inflammation, and circadian rhythms in neurodegenerative conditions.

referenceLipid assemblies are at the intersection of aging, proteostasis, and neurodegeneration, as described in the 2019 paper 'Lipid assemblies at the crossroads of aging, proteostasis, and neurodegeneration' published in Trends in Cell Biology.

Sleep Across the Lifespan: A Neurobehavioral Perspective link.springer.com Springer Feb 5, 2025 1 fact

referenceAndré et al. demonstrated that changes in REM sleep microstructure are related to greater neurodegeneration and amyloid deposition in aging.

U shaped association between sleep duration and long ... nature.com Nature by F Feng · 2025 1 fact

claimProlonged sleep duration may be an early manifestation of underlying neurodegeneration rather than a causal factor for cognitive decline.

Medicinal plants and human health: a comprehensive review of ... link.springer.com Springer Nov 5, 2025 1 fact

claimNanotechnology-based drug delivery systems enhance the bioavailability, target specificity, and therapeutic efficacy of medicinal plant compounds, particularly for treating cancer and neurodegeneration.

Chronic inflammation in the etiology of disease across the life span nature.com Nature Dec 5, 2019 1 fact

referenceMetabolic diseases, neuroinflammation, and neurodegeneration are linked through integrative neurobiology, as described in a 2015 study in Frontiers in Neuroscience.