concept

mutation

Also known as: mutation, mutations

Facts (9)

Sources

The function(s) of consciousness: an evolutionary perspective frontiersin.org Frontiers in Psychology Nov 25, 2024 2 facts

claimBiological consciousness is a product of evolution, which occurs through the gradual accumulation of genomic changes at the population level rather than sudden emergence via single mutations.

claimThe author posits that the transition from rudimentary consciousness to a consciousness consisting of multiple distinguishable contents likely requires natural selection acting across multiple generations at a population level, making the emergence of such complexity via fortuitous mutations vanishingly small.

Adaptive laboratory evolution – principles and applications for ... link.springer.com Springer Jul 1, 2013 2 facts

claimMutations serve as the basis for genetic change and the selection of improved phenotypes in both natural and laboratory environments.

claimMutations in amino acid catabolic processes and the stress response sigma factor, rpoS, are critical for acquiring a selective advantage in nutrient-starved conditions for Escherichia coli.

The Problem of Hard and Easy Problems cambridge.org Cambridge University Press Mar 31, 2023 1 fact

referenceEarly geneticists and developmental biologists attributed the function of determining wing development and body axis formation to the 'wingless' gene based on observed phenotypic differences between wild-type Drosophila and those with mutations at the wingless locus, as documented by Sharma (1973).

A Double-Edged Sword: Inflammation and Your Health - Cedars-Sinai cedars-sinai.org Cedars-Sinai Feb 12, 2021 1 fact

claimScientists hypothesize that mutation and inflammation are mutually reinforcing processes that can transform normal cells into tumors.

Mitochondria and the dynamic control of stem cell homeostasis link.springer.com Springer Apr 16, 2018 1 fact

claimThe use of various antioxidants failed to increase the efficiency of induced pluripotent stem cell (iPSC) reprogramming and did not ameliorate growth defects in iPSCs carrying mitochondrial DNA (mtDNA) mutations.

Editorial: Inflammation and chronic disease - Frontiers frontiersin.org Frontiers Jul 1, 2024 1 fact

claimMutations in age-related, clonal hematopoiesis of indeterminate potential (CHIP) increase the expression of inflammatory genes, which is associated with nearly double the risk of coronary artery disease.

Homeostatic medicine: a strategy for exploring health and disease link.springer.com Springer Sep 26, 2022 1 fact

claimRedundant mitochondrial DNA provides a reserve capacity that can reduce the impact of mutations on energy metabolism, according to Miller et al. (2003).